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Hunan Yuxin Pharmaceutical Co., Ltd.
Hunan Yuxin Pharmaceutical Co., Ltd.
23 YRS
Hunan, China
Main Products:
Betamethasone / Desonide / Budesonide / Clobetasol Propionate / Dutasteride / Halobetasol Propionate / Mometasone Furoate / Hydrocortisone / Cyproterone Acetate / Prednisone / Diflorasone / Finasteride / Deflazacort / Dienogest / Estrone / 2,3-Dichloro-5,6-Dicyano-1,4-Benzoquinone
Hunan, China
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Clobetasol Propionate / CAS 25122-46-7
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Clobetasol Propionate
Chinese Name:氯倍他索丙酸酯
Structural type:
CAS：25122-46-7
Molecular formula: C25H32ClFO5
Molecular weight: 466.97
Character: White powder
Usage: A dermatological drug
Typical Properties
Summary
Clobetasol propionate is a skin medicine. Topical application is suitable for chronic eczema, neurodermatitis, psoriasis, palmoplantar pustulosis, lichen planus, discoid lupus erythematosus and other glucocorticoid topical treatment of effective pruritus and non infectious inflammatory skin diseases. This product has a rapid effect, and it is a kind of highly effective topical corticosteroid Chinese medicine in clinical application. Its anti-inflammatory effect is 112.5 times of that of hydrocortisone, 2.3 times of that of betamethasone sodium phosphate and 18.7 times of that of fluoxetine. The systemic adverse reaction was 3 times as much as that of fluoxetine. Anhydrous sodium had retention effect and promoted the excretion of sodium and potassium.
CAS No.
25122-46-7
Formula
C25H32ClFO5
Molecular Mass
466.97000
Exact Mass
466.19200
PSA
80.67000
Logp
4.10310
IUPAC
[(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
SMILES
CCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CCl
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Hormones And Endocrine Drugs
Chemical and Physical Properties
Melting Point
195.5-197ºC
Density
1.28 g/cm3
Boiling Point
569ºC
Flash Point
297.9ºC
Appearance
White crystalline powder
Export information
HS Code
29372290
Export Rebate
13%
Export Formalities
Q
Risk Code
R36/37/38-62-53-48/20/21-61
Safety Label
Xi,T
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