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Anhui Sunhere Pharmaceutical Excipients Co.,Ltd.

24 YRS

Anhui, China

CNY 180.5 Million

90576 m²

500-1000 people

Main Products: Microcrystalline Cellulose / Polyacrylic Acid / Sodium Stearyl Fumarate

Anhui, China

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Sodium Stearyl Fumarate / CAS 4070-80-8

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Sodium Stearyl Fumarate

English Name: sodium stearyl fumarate

CAS No.: 4070-80-8

Molecular formula: C22H39NaO4

Molecular weight: 390.53

EINECS No.: 223-781-1

Introduction: sodium stearic fumarate is prepared by reacting stearic alcohol with maleic anhydride, isomerizing the reaction product and then forming salt. Sodium stearic fumarate is a hydrophilic lubricant used as a lubricant in pharmaceutical excipients. It can overcome many problems related to magnesium stearate, such as the main drug is affected and over lubricated; Forming a protective film in effervescent tablets can improve disintegration and promote dissolution, so as to improve bioavailability.

Uses: dough conditioner; Wheat flour treatment agent; Oxidant.

Typical Properties

Sodium stearate fumarate is a widely used and important pharmaceutical food excipient. During the metabolism of sodium stearate fumarate in animals, most of it can be absorbed and hydrolyzed to produce stearyl alcohol and stearic acid, and a small part can be directly and quickly metabolized out, which is non-toxic and non irritating. In the pharmaceutical field, sodium stearate fumarate is added to pharmaceutical preparations, which can be used as a lubricant for tablets and capsules, and can also form a protective film in effervescent tablets, which can solve the problems of stearate lubricants, improve drug disintegration and promote drug dissolution. In the field of food, FDA allows sodium stearate fumarate as a regulator and stabilizer to be directly added to foods for human consumption, such as various baked foods, flour thickened foods, dried potatoes and processed grains.

CAS No.

4070-80-8

Formula

C22H39NaO4

Molecular Mass

390.53200

Exact Mass

390.27500

PSA

77.43000

Logp

5.39890

IUPAC

sodium;(E)-4-octadecoxy-4-oxobut-2-enoate

SMILES

CCCCCCCCCCCCCCCCCCOC(=O)/C=C/C(=O)[O-].[Na+]

Matter Classification

organic

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