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Zhejiang Hisun Pharmaceutical Co., Ltd.

69 YRS

Zhejiang, China

CNY 1196.0 Million

612720 m²

Over 1000 people

Main Products: Fludarabine Phosphate / Mesna / Mitomycin / Actinomycin D / Doxorubicin Hydrochloride / Idarubicin Hydrochloride / Epirubicin Hydrochloride / Anastrozole / Cladribine / Daunorubicin Hydrochloride / Letrozole / Cytarabine / Bleomycin Sulfate / Bicalutamide / Cyclophosphamide / Rifamycin-O

Zhejiang, China

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Cytarabine / CAS 147-94-4

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Cytarabine

CAS No.: 147-94-4

Molecular formula: C9H13N3O5

Molecular weight: 243.21

Melting point: 214 ℃

Appearance: white fine acicular crystal or crystalline powder

Application: antitumor drugs

Typical Properties

Cytarabine is a kind of purine nucleoside antiviral drug which is extracted from Streptomyces culture medium and synthesized by chemical method. It is slightly soluble in water, and its monophosphate is easily soluble in water. It can inhibit HSV1 and HSV2, hepatitis B virus, varicella zoster virus and cytomegalovirus, but has no effect on smallpox virus, adenovirus, other DNA or RNA viruses, bacteria and fungi. At present, the exact mechanism of cytosine arabinoside antiviral has not been fully elucidated, which is mainly related to the inhibition of virus replication. Drugs and their metabolites block the synthesis of viral DNA by inhibiting viral DNA polymerase, while drugs only penetrate into viral DNA molecules in a very small amount. Cytarabine is also one of the most effective drugs for the treatment of acute non lymphocytic myeloid leukemia in China.

CAS No.

147-94-4

Formula

C9H13N3O5

Molecular Mass

243.21700

Exact Mass

243.08600

PSA

130.83000

Logp

-1.98180

IUPAC

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

SMILES

C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O

Matter Classification

organic

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