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Shanghai Jinhe BIO-PHARMACEUTICAL Co., Ltd.

24 YRS

Shanghai, China

CNY 3.4 Million

19980 m²

100-500 people

Main Products: Paclitaxel / Docetaxel Trihydrate / 10-Deacetylbaccatin III / Docetaxel / Cabazitaxel / Baccatine III

Shanghai, China

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Cabazitaxel / CAS 183133-96-2

OVERVIEW

Packaging

5 KG/BOTTLE

Lead Time

14-30 days

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DESCRIPTION

Cabazitaxel

Product introduction:

Cabataxel is a microtubule inhibitor, which is suitable for the combination with prednisone or prednisolone in the treatment of patients with hormone refractory metastatic prostate cancer with docetaxel containing treatment regimen. It has achieved more accurate treatment in the whole treatment process. It acts by disrupting the microtubule network essential for mitotic and interphase cell function and causes inhibition of cell division and cell death.

CAS：183133-96-2

Molecular formula: C₄₅H₅₇NO₁₄

Molecular weight: 835.93

Character: White or off white powder, almost insoluble in water and soluble in ethanol.

Product purpose: Carbataxel combined with prednisone is used to treat hormone refractory metastatic prostate cancer previously treated with docetaxel containing regimen.

Typical Properties

Carbataxel combined with prednisone is used to treat hormone refractory metastatic prostate cancer previously treated with docetaxel containing regimen.

CAS No.

183133-96-2

Formula

C45H57NO14

Molecular Mass

835.93200

Exact Mass

835.37800

PSA

202.45000

Logp

4.95870

IUPAC

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

SMILES

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC

Matter Classification

organic

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