4-chloropyrrolopyrimidine is an important pharmaceutical intermediate, which is used as an intermediate for the bulk drug of tofacinib in the treatment of adult patients with moderate to severe rheumatoid arthritis, such as methotrexate underreaction or intolerance. 4-chloropyrrolopyrimidine is also an important raw material for the development of many antibacterial, anti-tumor, anti vertebral worms and other drugs.
CAS No.
3680-69-1
Formula
C6H4ClN3
Molecular Mass
153.56900
Exact Mass
153.00900
PSA
41.57000
Logp
1.61130
IUPAC
4-chloro-7H-pyrrolo[2,3-d]pyrimidine
SMILES
C1=CNC2=C1C(=NC=N2)Cl
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Pharmaceutical Intermediates Auxiliary > Other Auxiliary Agent